Azamulin

CAS: 76530-44-4

Ref. 3D-AA18059

Product Information

• Name: Azamulin
• Synonyms: 14-O-(5-(2-Amino1,3,4-triazolyl)thioacetyl)dihydromutilinAntibiotic TDM 85-530SA 85530b, Azamulin [INN], ((5-Amino-s-triazol-3-yl)thio)acetic acid, 8-ester with (3aS,4R,5S,6R,8R,9R,9aR,10R)-6-ethyloctahydro-5,8-dihydroxy-4,6,9,10-tetramethyl-3a,9-propano-3aH-cyclopentacycloocten-1(4H)-one, ((5-Amino-s-triazol-3-yl)thio)acetic acid, 8-ester with (3aS,4R,5S,6R,8R,9aR,10R)-6-ethyloctahydro-5,8-dihydroxy-4,6,9,10-tetramethyl-3a,9-propano-3aH-cyclopentacycloocten-1(4H)-one, (3aS,4R,5S,6R,8R,9R,9aR,10R)-6-Ethyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propanocyclopentacycloocten-8-yl ((5-amino-1,2,4-triazol-3-yl)thio)acetat, Azamulinum, Unii-875Aq866X1, (3aS,4R,5S,6R,8R,9R,9aR)-6-ethyl-5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-3a,9-propanocyclopenta[8]annulen-8-yl [(5-amino-1H-1,2,4-triazol-3-yl)sulfanyl]acetate

Description

Azamulin is a p-glycoprotein (p-gp) inhibitor that belongs to the family of antimicrobial agents. It has been shown to have an inhibitory effect on drug efflux mediated by p-gp, which is a membrane protein that pumps out drugs from cells. Azamulin also inhibits the production of ATP in vitro and has been shown to be active against Gram-positive and Gram-negative bacteria, including those resistant to fluconazole. This drug has been tested in vivo using human pharmacokinetic studies, but there are no toxicity studies or interactions with other medications.

• Brand: Biosynth

Chemical properties

• Molecular weight: 478.65 g/mol
• Formula: C₂₄H₃₈N₄O₄S
• Purity: Min. 95%
• Color/Form: Solid