(-)-Nicotine ditartrate

CAS: 65-31-6

Ref. 3D-AAA06531

Product Information

• Name: (-)-Nicotine ditartrate
• Synonyms: (-)-Nicotine hydrogen (+)-tartrate, 3-(1-Methylpyrrolidin-2-Yl)Pyridine 2,3-Dihydroxybutanedioate (1:1), 3-[(2S)-1-methylpyrrolidin-2-yl]pyridine 2,3-dihydroxybutanedioate (salt), 3-[(2S)-1-methylpyrrolidin-2-yl]pyridine bis(2,3-dihydroxybutanedioate) (salt), NSC 97238, Nicotine acid tartrate, Nicotine bitartrate, Nicotine tartrate, Nicotine, tartrate (1:2), Np002, Pyridine, 3-(1-methyl-2-pyrrolidinyl)-, (S)-, [R-(R*,R*)]-2,3-dihydroxybutanedioate (1:2), Pyridine, 3-[(2S)-1-methyl-2-pyrrolidinyl]-, (2R,3R)-2,3-dihydroxybutanedioate (1:2), S-(-)-Nicotine hydrogen-(+)-tartrate

Description

(-)-Nicotine ditartrate is a polymorphic form of nicotine. It is a hydrogen tartrate salt with the chemical formula C10H14N2O4·H2O. (-)-Nicotine ditartrate has been shown to improve locomotor activity and reduce cortisol concentration in mice. In addition, this compound has been shown to inhibit oxidative injury in mice by reducing reactive oxygen species production. (-)-Nicotine ditartrate is also able to inhibit glutamate release from nerve terminals, which may be due to its ability to stimulate nicotinic acetylcholine receptors (nAChRs). Further, it can induce apoptosis in cancer cells through activation of the MCL-1 protein and inhibition of cholinergic neurotransmission. This drug can also be used as an electrochemical impedance spectroscopy probe for the detection of reactive oxygen species.

• Brand: Biosynth

Chemical properties

• Molecular weight: 462.41 g/mol
• Formula: C₁₀H₁₄N₂·2C₄H₆O₆
• Purity: Min. 95%