PKF118-310

Ref. 3D-AAA08482

Product Information

• Name: PKF118-310
• Brand: Biosynth
• Description: PKF118-310 is a basic protein that has been shown to have significant cytotoxicity against the human cancer cell line K562. PKF118-310 has been shown to induce apoptosis in these cells by binding to cyclin D2, which is a protein involved in the cell cycle. PKF118-310 also inhibits production of prostaglandin E2 and tumor necrosis factor (TNF), which are important mediators of inflammation. PKF118-310 induces phase II detoxification enzymes such as glutathione reductase, cytochrome P450, and esterases through the activation of transcriptional factors such as NF-κB and AP-1. These enzymes are responsible for metabolizing toxic compounds from the body.

Chemical properties

• Molecular weight: 193.16 g/mol
• Formula: C₇H₇N₅O₂
• Purity: Min. 95%