N-Acetylsulfathiazole

CAS: 127-76-4

Ref. 3D-AAA12776

Product Information

• Name: N-Acetylsulfathiazole
• Synonyms: 2-(p-Acetamidobenzenesulfonamido)thiazole, AST, Acetamide, N-[4-[(2-thiazolylamino)sulfonyl]phenyl]-, Acetanilide, 4′-(2-thiazolylsulfamoyl)-, Acetylsulfathiazole, N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide, N-[4-[(2-Thiazolylamino)sulfonyl]phenyl]acetamide, N4-acetylsulfathiazole, N⁴-Acetylsulfathiazole, Sulfathiazole, acetyl-, p-Acetylamino-N-(2-thiazolyl)benzenesulfonamide

Description

N-Acetylsulfathiazole is a sulfa drug that acts as an inhibitor of bacterial growth. It reacts with sulfonic acids in the receptor molecule and forms hydrogen chloride, which inhibits bacterial growth by denaturing proteins. N-Acetylsulfathiazole has been shown to be effective against bacteria such as E. coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus pyogenes, and Salmonella enterica. This antibiotic binds to the active site of the enzyme dihydropteroate synthase and inhibits pyrimidine synthesis by competing with para-aminobenzoic acid (PABA) for binding sites on the enzyme. The formation of PABA is necessary for the synthesis of folic acid (vitamin B9). N-Acetylsulfathiazole is also used to treat vitamin B6 deficiency caused by

• Brand: Biosynth

Chemical properties

• Molecular weight: 297.4 g/mol
• Formula: C₁₁H₁₁N₃O₃S₂
• Purity: Min. 95%