Benzo[h]quinoline

CAS: 230-27-3

Ref. 3D-AAA23027

Product Information

• Name: Benzo[h]quinoline
• Synonyms: 4-Azaphenanthrene, 7,8-Benzo[h]quinoline, 7,8-Benzoquinoline~alpha-Naphthoquinoline, NSC 16033, alpha-Benzoquinoline, alpha-Naphthoquinoline, Α-Naphthoquinoline, α-Benzoquinoline
• CAS: 230-27-3

Description

Benzo[h]quinoline is a type of aromatic compound that forms stable complexes with protonated nitrogen atoms. The hydrogen bond between the benzo[h]quinoline and protonated nitrogen atom is a significant factor in the stability of these complexes. Benzo[h]quinoline also has cytotoxic properties, as observed by its significant cytotoxicity to cancer cells in the WST-1 assay. It has been shown to bind to proteins, such as DNA polymerase β and topoisomerase II, through an intramolecular hydrogen bond. The macrocyclic structure of benzo[h]quinoline allows it to be highly soluble in organic solvents, such as trifluoroacetic acid. The kinetic energy required for this complexation is significantly less than that required for other types of compounds with similar structures.

• Brand: Biosynth

Chemical properties

• Molecular weight: 179.22 g/mol
• Formula: C₁₃H₉N
• Purity: Min. 95%