Violacein

CAS: 548-54-9

Ref. 3D-AAA54854

Product Information

• Name: Violacein
• Synonyms: (3E)-3-[1,2-Dihydro-5-(5-hydroxy-1H-indol-3-yl)-2-oxo-3H-pyrrol-3-ylidene]-1,3-dihydro-2H-indol-2-one, (E)-3-[1,2-Dihydro-5-(5-hydroxy-1H-indol-3-yl)-2-oxo-3H-pyrrol-3-ylidene]-1,3-dihydro-2H-indol-2-one, 1H-indol-5-ol, 3-[(3E)-2-hydroxy-3-(2-hydroxy-3H-indol-3-ylidene)-3H-pyrrol-5-yl]-, 2-Indolinone, 3-(2-(5-hydroxyindol-3-yl)-5-oxo-2-pyrrolin-4-ylidene)-, 2H-Indol-2-one, 3-[1,2-dihydro-5-(5-hydroxy-1H-indol-3-yl)-2-oxo-3H-pyrrol-3-ylidene]-1,3-dihydro-, (E)-, 2H-indol-2-one, 3-[1,2-dihydro-5-(5-hydroxy-1H-indol-3-yl)-2-oxo-3H-pyrrol-3-ylidene]-1,3-dihydro-, (3E)-, 3-(2-(5-Hydroxyindol-3-yl)-5-oxo-2-pyrrolin-4-ylidene)-2-indolinone, 3-[2-(5-Hydroxyindol-3-yl)-5-oxopyrrolin-4-ylidene]oxindole, 5-(5-Hydroxy-3-indolyl)-3-(3-oxindolylidene)-2-oxopyrroline, 548-54-9, Oxindole, 3-[2-(5-hydroxyindol-3-yl)-5-oxo-2-pyrrolin-4-ylidene]-, V 9389

Description

Violacein is a model system for studying the effects of hydroxyl groups on cell lysis. It is a fatty acid that contains nitrogen atoms and has antimicrobial properties. Violacein has been shown to cause the loss of mitochondrial membrane potential in HL-60 cells, which may be due to its ability to act as a multidrug efflux pump inhibitor. Violacein also exhibits antimicrobial activity against several bacterial strains, including MRSA and methicillin-sensitive Staphylococcus aureus (MSSA). In addition, violacein has been shown to induce cell lysis in vitro via the degradation of proteins and lipids in the cytoplasm.

• Brand: Biosynth

Chemical properties

• Molecular weight: 343.3 g/mol
• Formula: C₂₀H₁₃N₃O₃
• Purity: Min. 95%
• Color/Form: Powder