2-(Hydroxymethyl)benzoic acid

CAS: 612-20-4

Ref. 3D-AAA61220

Product Information

• Name: 2-(Hydroxymethyl)benzoic acid
• Synonyms: 2-Carboxybenzyl alcohol, Benzoic acid, 2-(hydroxymethyl)-, Benzoic acid, 2-(hydroxymethyl)- (9CI), Nsc 30638, alpha-Hydroxy-o-toluic acid, o-(Hydroxymethyl)benzoic acid, o-Carboxybenzyl alcohol, o-Toluic acid, alpha-hydroxy- (8CI), o-Toluic acid, α-hydroxy-, α-Hydroxy-o-toluic acid
• CAS: 612-20-4

Description

2-(Hydroxymethyl)benzoic acid is a molecule that can be found in the human liver. It is a metabolite of the drug 2-hydroxybenzoic acid, which inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. 2-(Hydroxymethyl)benzoic acid also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.

• Brand: Biosynth

Chemical properties

• Molecular weight: 152.15 g/mol
• Formula: C₈H₈O₃
• Purity: Min. 95%