2-(Dimethylamino)ethane-1-sulfonic acid

CAS: 637-95-6

Ref. 3D-AAA63795

Product Information

• Name: 2-(Dimethylamino)ethane-1-sulfonic acid
• Brand: Biosynth
• Description: 2-(Dimethylamino)ethane-1-sulfonic acid (DMAES) is a sulfonamide drug that binds to basic proteins and has been used in the treatment of microbial infections. DMAES has been shown to bind to human serum albumin, which may be due to its ability to form a covalent bond with the sulfur on the protein. The binding constant for DMAES with human serum albumin is about 5x10 M. The clinical response in patients treated with DMAES was found to depend on the binding constant between DMAES and human serum albumin. The binding constants for DMAES with other proteins have also been studied. These include erythrocyte membrane protein, myelin basic protein, and ganglioside GM1. In addition, it has been found that DMAES can bind to ganglia cells of rat brain tissue by forming a covalent bond with amino acids such as lysine residues

Chemical properties

• Molecular weight: 153.2 g/mol
• Formula: C₄H₁₁NO₃S
• Purity: Min. 95%
• Color/Form: Powder