trans-Vaccenic acid

CAS: 693-72-1

Ref. 3D-AAA69372

Product Information

• Name: trans-Vaccenic acid
• Synonyms: (11E)-11-Octadecenoic acid, (E)-11-Octadecenoic acid, (E)-Octadec-11-ensaure, (E)-octadec-11-enoic acid, 11(E)-Octadecenoic acid, 11-Octadecenoic acid, (11E)-, 11-Octadecenoic acid, (E)-, 11-trans-Octadecenoic acid, Acide (E)-octadec-11-enoique, Vaccenic acid, acido (E)-octadec-11-enoico, trans-11-Octadecenoic acid, trans-Δ11-Octadecenoic acid, trans-Δ¹¹-Octadecenoic acid

Description

Trans-vaccenic acid is an unsaturated fatty acid that is found in milk fat. It has been shown to inhibit multiple enzymes and induce apoptosis in human colonic cells. Trans-vaccenic acid has been shown to inhibit the activity of three different enzymes, phospholipase A2, cyclooxygenase, and lipoxygenase, which are involved in the inflammatory bowel disease pathway. Trans-vaccenic acid also inhibits tumor necrosis factor alpha (TNF-α) production by lipopolysaccharide (LPS)-activated macrophages and decreases the expression of proinflammatory genes such as interleukin-1β. This anti-inflammatory effect may be due to trans-vaccenic acid's ability to inhibit fatty acid uptake into liver cells and decrease cellular inflammation.

• Brand: Biosynth

Chemical properties

• Molecular weight: 282.46 g/mol
• Formula: C₁₈H₃₄O₂
• Purity: Min. 95%