1-(3-Nitrophenyl)-2-thiourea

CAS: 709-72-8

Ref. 3D-AAA70972

Product Information

• Name: 1-(3-Nitrophenyl)-2-thiourea
• Brand: Biosynth
• Description: 1-(3-Nitrophenyl)-2-thiourea is a small molecule inhibitor of the transporter protein SLC5A8, which transports nitrates from the blood to the kidneys. 1-(3-Nitrophenyl)-2-thiourea inhibits this transporter in a systemically active fashion and selectively targets renal epithelial cells. This analog has been shown to be effective against some inherited disorders associated with mutations in SLC5A8. 1-(3-Nitrophenyl)-2-thiourea is believed to inhibit transport by binding to an allosteric site on SLC5A8, but its precise mechanism of action remains unclear.

Chemical properties

• Molecular weight: 197.22 g/mol
• Formula: C₇H₇N₃O₂S
• Purity: Min. 95%