2,6-Dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxamide
CAS: 769-97-1
Ref. 3D-AAA76997
1g | 1,041.00 € | ||
100mg | 262.00 € |
Product Information
2,6-Dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxamide (DOTPC) is a monomer that can be used to stabilize duplexed and triplexed nucleic acid structures. DOTPC binds to the amine groups in RNA and DNA molecules, which stabilizes the structure of nucleic acids by preventing the formation of undesirable hydrogen bonds between nucleotides. The compound has been shown to be effective in hybridizing duplexes and triplexes with complementary strands containing uracil or thymine bases. DOTPC is synthesized from orotic acid by reacting it with an amine in a carboxamide reaction.
Chemical properties
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