Product Information
- Benzoic acid, 2-hydroxy-5-nitro-, hydrazide
- 2-Hydroxy-5-nitrobenzoic acid hydrazide
- Salicylic acid, 5-nitro-, hydrazide
- (2-Hydroxy-5-nitrobenzoyl)hydrazine
- 5-Nitrosalicyl hydrazide
2-Hydroxy-5-nitrobenzohydrazide is an antibacterial agent that binds to the hydroxylase domain of bacterial 7-ethoxycoumarin hydroxylase, a key enzyme in the synthesis of tetranuclear cofactors. It forms a coordination geometry with the metal ions that are required for this enzyme, thereby blocking its activity. 2-Hydroxy-5-nitrobenzohydrazide has been shown to be effective against bacteria such as Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa. This compound also has a specific affinity for mononuclear bacteria such as Proteus mirabilis and Klebsiella pneumoniae.
2-Hydroxy-5-nitrobenzohydrazide is not active against Gram positive bacteria due to its lack of binding affinity for the epoxide hydrolase domain of bacterial 7-ethoxycou
Chemical properties
Technical inquiry about: 3D-AAA94632 2-Hydroxy-5-nitrobenzohydrazide
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