Product Information
BI8622 is a small molecule that binds to caspase-1 and inhibits the enzyme's activity by preventing its activation. BI8622 also targets enzymes involved in the ubiquitin proteasome pathway, which are responsible for protein degradation. This drug has been shown to inhibit the expression of IL-1β and IL-18, which are molecules important in immune response. BI8622 has also been shown to reduce acute kidney injury by inhibiting DNA replication, which leads to cell death.
Chemical properties
Technical inquiry about: 3D-AAD03674 BI8622
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