Cefuroxime axetil

CAS: 64544-07-6

Ref. 3D-AC19882

Product Information

• Name: Cefuroxime axetil
• Synonyms: (6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-furanyl)-2-(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en e-2-carboxylic acid 1-(acetyloxy)ethyl esterAltacefBioracef, 1-(acetyloxy)ethyl (6R,7R)-3-[(carbamoyloxy)methyl]-7-{[(2E)-2-furan-2-yl-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-(((aminocarbonyl)oxy)methyl)-7-((2-furanyl(methoxyimino)a cetyl)-amino)-8-oxo-, 1-(acetyloxy)ethyl ester, (6R-(6alpha,7beta(Z)))-, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-furanyl)-2-(methoxyimino)acetyl]amino]-8-oxo-, 1-(acetyloxy)ethyl ester, (6R,7R)-, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-furanyl(methoxyimino)acetyl]amino]-8-oxo-, 1-(acetyloxy)ethyl ester, (6R,7R)-, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(aminocarbonyl)oxy]methyl]-7-[[2-furanyl(methoxyimino)acetyl]amino]-8-oxo-, 1-(acetyloxy)ethyl ester, [6R-[6α,7β(Z)]]-, Altacef, Axoril, Bioracef, Bioxime, Cci 15641, Cefaks, Cefazine, Ceftin, Cefurax, Cefuroxime 1-Acetoxymethyl Ester, Cefuroxime 1-acetoxyethyl ester, Cefuroxine 1-acetoxyethyl ester, Cepazine, Elobact, Forcef, Kefurox, Oraxim, Ximos, Xorimax, Zinacef, Zinat, Zinnat

Description

Cefuroxime axetil is a prodrug of cefuroxime, a broad-spectrum beta-lactam antibiotic. It is used to treat bacterial infections such as streptococcal pharyngitis, acute sinusitis, and uncomplicated skin and soft tissue infections. Cefuroxime axetil has an analytical method that can be used to determine the rate constant for its hydrolysis by ileal mucosa in vitro. This drug has been shown to have antibacterial efficacy against a wide range of bacteria and does not inhibit the production of cytokines (IL-2 receptor) or other inflammatory mediators (toll-like receptor). There are no known drug interactions with this drug, although it has been shown to cause toxic epidermal necrolysis when administered intravenously in combination with nonsteroidal anti-inflammatory drugs.

• Brand: Biosynth

Chemical properties

• Molecular weight: 510.48 g/mol
• Formula: C₂₀H₂₂N₄O₁₀S
• Purity: Min. 98 Area-%
• Color/Form: Powder