Product Information
Name:Doxorubicin HCl
Synonyms:
- Adriamycin ADR Doxorubicin DOX Caelyx (8S,10S)-10-[(3-Amino-2,3 ,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8
- 11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione hydrochloride
Brand:Biosynth
Description:Doxorubicin (DOX) is an antineoplastic chemotherapy drug used to treat breast, ovarian and pancreatic cancers. It is an antitumor antibiotic that inhibits DNA topoisomerase II. DOX interferes with the topoisomerase II-mediated repair of DNA causing accumulation of mutations. It also leads to the generation of reactive oxygen species (ROS), which further damage DNA as well as proteins and membranes. However, the compound presents with a risk of developing cardiomyopathy as well as drug resistance. Pegylated liposomal doxorubicin has also been developed to treat breast and ovarian cancers, myeloma, and HIV-related Kaposi’s sarcoma.
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Chemical properties
Molecular weight:579.98 g/mol
Formula:C27H29NO11·HCl
Purity:Min. 98 Area-%
Color/Form:Red Powder
Technical inquiry about: Doxorubicin HCl
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