7-O-Demethyl rapamycin

CAS: 151519-50-5

Ref. 3D-AD21012

Product Information

• Name: 7-O-Demethyl rapamycin
• Synonyms: 7-O-Demethyl cypher7-O-Demethyl rapammune7-O-Demethyl sirolimus
• Brand: Biosynth
• Description: 7-O-Demethyl rapamycin is a macrolide compound, which is a derivative of rapamycin, originally sourced from the bacterial species *Streptomyces hygroscopicus*. This compound operates by binding to the FK506-binding protein 12 (FKBP12), forming a complex that inhibits the mammalian target of rapamycin (mTOR) pathway. This inhibition interferes with cellular processes such as cell growth, proliferation, and survival by altering the phosphorylation state of downstream targets.

Chemical properties

• Molecular weight: 900.15 g/mol
• Formula: C₅₀H₇₇NO₁₃
• Purity: 80%Min