Danofloxacin

CAS: 112398-08-0

Ref. 3D-AD35286

Product Information

• Name: Danofloxacin
• Synonyms: Advocin(R), 1-Cyclopropyl-6-fluoro-1,4-dihydro-7-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl]-4-oxo-3-quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-7-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, 2,5-Diazabicyclo[2.2.1]heptane, 3-quinolinecarboxylic acid deriv., 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-7-(5-methyl-2,5-diazabicyclo(2.2.1)hept-2-yl)-4-oxo-, (1S)-, 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-7-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl]-4-oxo-, Advocin, Advocip, Dafloxacin, Danofloxacin [INN:BAN], Danofloxacine, Danofloxacine [INN-French], Danofloxacino, Danofloxacino [INN-Spanish], Danofloxacinum, Danofloxacinum [INN-Latin], Unii-24Cu1Ys91D

Description

Danofloxacin is a fluoroquinolone antibiotic that inhibits the DNA gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. It binds to bacterial 16S ribosomal RNA and inhibits protein synthesis, leading to cell death by inhibiting the production of proteins vital for cell division. Danofloxacin has been shown to be effective against methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium perfringens, although is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex. Danofloxacin has shown anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 357.38 g/mol
• Formula: C₁₉H₂₀FN₃O₃
• Purity: Min. 95%
• Color/Form: Powder