Desmethyl doxorubicin oxalate

CAS: 69401-50-9

Ref. 3D-AD64742

Product Information

• Name: Desmethyl doxorubicin oxalate
• Synonyms: 14-Hydroxy Carminomycin
• Brand: Biosynth
• Description: Desmethyl doxorubicin oxalate is an anthracycline-type chemotherapeutic agent, which is derived from the naturally occurring antibiotic doxorubicin. This compound comprises a desmethylated form of doxorubicin combined with oxalate. Its mode of action involves intercalating DNA strands and inhibiting topoisomerase II, thereby disrupting DNA replication and transcription. This interference leads to the inhibition of cancer cell proliferation and induces apoptosis.

Chemical properties

• Molecular weight: 529.49 g/mol
• Formula: C₂₆H₂₇NO₁₁
• Purity: Min. 95%
• InChI: InChI=1S/C26H27NO11/c1-9-21(31)12(27)5-16(37-9)38-14-7-26(36,15(30)8-28)6-11-18(14)25(35)20-19(23(11)33)22(32)10-3-2-4-13(29)17(10)24(20)34/h2-4,9,12,14,16,21,28-29,31,33,35-36H,5-8,27H2,1H3
• InChI key: InChIKey=XELCDTXCWBAMFX-UHFFFAOYSA-N
• SMILES: CC1OC(OC2CC(O)(C(=O)CO)Cc3c(O)c4c(c(O)c32)C(=O)c2c(O)cccc2C4=O)CC(N)C1O