AZ-1355
CAS: 75451-07-9
Ref. 3D-ADA45107
| 1mg | To inquire | ||
| 5mg | To inquire | ||
| 10mg | To inquire | ||
| 25mg | To inquire | ||
| 50mg | To inquire |
Product Information
- Az-1355
- 10,11-Dihydro-4-methoxydibenz[b,f][1,4]oxazepine-8-carboxylic acid ethyl ester
- Ethyl 4-Methoxy-10,11-Dihydrodibenzo[B,F][1,4]Oxazepine-8-Carboxylate
AZ-1355 is a novel, orally bioavailable, small molecule inhibitor of collagen-specific proteinase (MMP-1) that has been shown to be effective in preventing the development of cerebral amyloidosis in hamsters. AZ-1355 is orally bioavailable and penetrates the blood brain barrier, thus reducing the amount of MMP-1 that can enter the brain. This drug has also been shown to reduce cardiac collagen deposition and improve endothelial function. AZ-1355 has not been tested on humans or animals for its potential toxicity, but it does have a toxic profile in vitro. This drug has also been shown to have damaging effects on platelets and cause death in cultured cells.
Chemical properties
Technical inquiry about: 3D-ADA45107 AZ-1355
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