Product Information
- (R)-2-Amino-3-(4-imidazolyl)propanol dihydrochloride
D-Histidinol dihydrochloride is a non-nucleoside inhibitor of phosphodiesterase enzymes. It has shown to be an effective inhibitor of topoisomerase II and topoisomerase IV, which are essential for DNA replication, repair and recombination. D-Histidinol dihydrochloride has been shown to inhibit the phosphodiesterase activity of several different types of cellular enzymes, including PDE1A4, PDE2A4 and PDE3A4. This drug also has shown to have some structural similarities with the nucleoside diphosphate analogs cAMP and cGMP. D-Histidinol dihydrochloride may be useful in the treatment of diseases that involve damage to DNA or cells.
Chemical properties
Technical inquiry about: 3D-ADA61484 D-Histidinol dihydrochloride
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