Cycloshizukaol A
CAS: 150033-85-5
Ref. 3D-AGA03385
| 5mg | To inquire | ||
| 10mg | To inquire | ||
| 25mg | To inquire | ||
| 50mg | To inquire |
Product Information
- 4,6:10,12-Diethanobiscyclopropa[3,4]cyclopenta[1,2-a:1',2'-g]cyclododecene-3,9-dicarboxylicacid, 1,1a,2,3,6,6a,7,7a,8,9,12,12a-dodecahydro-13,15-dihydroxy-3,6,9,12-tetramethyl-14,16-dioxo-,dimethyl ester, (1aS,3R,6S,6aR,7aS,9R,12S,12aR,13R,15R)- (9CI)
- 4,6:10,12-Diethanobiscyclopropa[3,4]cyclopenta[1,2-a:1',2'-g]cyclododecene-3,9-dicarboxylicacid, 1,1a,2,3,6,6a,7,7a,8,9,12,12a-dodecahydro-13,15-dihydroxy-3,6,9,12-tetramethyl-14,16-dioxo-,dimethyl ester, [1aS-(1aR*,3S*,6R*,6aS*,7aR*,9S*,12R*,12aS*,13S*,15S*)]-
Cycloshizukaol A is a natural product that has been shown to inhibit the production of TNF-α by human monocytes. It also inhibits the proliferation of HL-60 cells, which are cells from the human promyelocytic leukemia cell line. Cycloshizukaol A has been shown to have anti-inflammatory properties and can be used for the treatment of inflammatory diseases. Cycloshizukaol A has been shown to inhibit fatty acid synthesis in liver cancer cells by blocking activity at the level of transcription and translation. The molecule also inhibits fatty acid synthesis in THP-1 cells, which are human monocytes derived from a patient with myelodysplastic syndrome.
Chemical properties
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