Product Information
Name:SBE13
Controlled Product
Brand:Biosynth
Description:SBE13 is a molecule that inhibits the activity of the proteasome. It has been shown to have anti-cancer effects in vitro and in vivo, with an effective dose for inhibiting cancer cell proliferation at 1 μM. SBE13 binds to the 5-membered heteroaryl ring of plk1 and inhibits its kinase activity. This inhibition leads to decreased phosphorylation of glycogen synthase kinase 3β (GSK3β) and increased phosphorylation of cyclin D1, leading to a decrease in the rate of cell cycle progression. SBE13 also inhibits caco-2 cells proliferation, cervical cancer cells proliferation, and mcf-7 cell growth by interfering with cell cycle progression.
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Chemical properties
Molecular weight:442.9 g/mol
Formula:C24H27ClN2O4
Purity:Min. 95%
Technical inquiry about: SBE13
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