Product Information
α-Conotoxin MII is a peptide toxin that binds to nicotinic acetylcholine receptors. α-Conotoxin MII can inhibit the activity of acetylcholine at the neuromuscular junction, leading to muscle paralysis. It has been shown to be a potent antagonist against nicotinic acetylcholine receptors in rat caudate putamen and human carcinoma cell lines. This peptide also inhibits nicotine-induced locomotor activity in rats and nicotine binding in rat liver cells. α-Conotoxin MII also blocks the ryanodine receptor, which is involved in calcium release from intracellular stores, leading to inhibition of cell proliferation and decreased cancer cell growth.
Chemical properties
Technical inquiry about: 3D-AHA73593 α-Conotoxin MII
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