Product Information
Kras inhibitor-9 is a research tool that is used in cell biology, pharmacology and ion channels. It has been shown to inhibit the activity of KrasG12D and other GTPase proteins. Kras inhibitor-9 binds to the peptide sequence DQPYFQN near the N terminus of KrasG12D, blocking its interaction with other proteins. This binding prevents KrasG12D from activating downstream signaling pathways, including MAPK/ERK kinases and Akt kinases. Kras inhibitor-9 may be able to inhibit tumor growth by blocking activation of oncogenes such as Kras and p53.
Chemical properties
Technical inquiry about: 3D-AMA80971 Kras inhibitor-9
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