21-Norrapamycin

CAS: 156223-31-3

Ref. 3D-AN181380

Product Information

• Name: 21-Norrapamycin
• Brand: Biosynth
• Description: 21-Norrapamycin is a macrocyclic lactone antibiotic, which is derived from the bacterium Streptomyces hygroscopicus. Its chemical structure is closely related to that of rapamycin, a well-known immunosuppressant. The mode of action of 21-Norrapamycin involves the inhibition of the mechanistic target of rapamycin (mTOR) signaling pathway. By binding to the FK506-binding protein 12 (FKBP12), it forms a complex that then inhibits mTOR, a crucial regulator of cell growth, proliferation, and survival.

Chemical properties

• Molecular weight: 900.1 g/mol
• Formula: C₅₀H₇₇NO₁₃
• Purity: Min. 95%