Norfloxacin

CAS: 70458-96-7

Ref. 3D-AN26450

Product Information

• Name: Norfloxacin
• Synonyms: 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acidBaccidalBarazan, 1,4-Dihydro-1-Ethyl-6-Fluoro-4-Oxo-7-(1-Piperazinyl)-3-Quinolinecarboxylic Acid, 1-Ethyl-6-Fluoro-4-Oxo-7-Piperazin-1-Yl-Quinoline-3-Carboxylic Acid, 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid, 1-Ethyl-6-fluoro-1,4-dihydro-7-(1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid, 1-Ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid, 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid, 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid, 2-Hydroxypropanoic Acid, 3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, 4803P, Am 715, Amicrobin, Baccidal, Barazan, Barotham, Chibroxin, Chibroxine, Chibroxol, Esclebin, Floxacin, Floxacin 400, Fulgram, Gonorcin, Lexinor, Mk 0366, N-Demethylpefloxacin, N-Desmethylpefloxacin, Neofloxacin, Neofloxin, Noflo, Nofocin, Nolicin, Noracin, Noraxin, Norbid, Norflox, Norflox 400, Norfloxacin Bayvit, Norfloxacine, Norfloxacine EG, Norfloxacine Ratiopharm, Norfloxacine Teva, Norfloxacino, Norfloxin, Norilet, Normax, Norocin, Noroxacine, Noroxin, Noroxine, Norphloxacine, Norxacin, Renosept, Sebercim, Spectrama, Urekacin, Uriflox, Uroflox, Urotrobel, Uroxacin, Utin, Utinor, Zoroxin

Description

Norfloxacin is a fluoroquinolone antibiotic that inhibits the activity of bacterial nitrate reductase. Norfloxacin has shown inhibitory properties against tetracycline-resistant bacteria and has been used for the treatment of urinary tract infections. Norfloxacin is also active against Gram-positive bacteria, such as Staphylococcus aureus. The rate constant for the inhibition of norfloxacin was determined by an electrochemical impedance spectroscopy assay in which wild-type strains of E. coli were grown in a phosphate buffer solution containing norfloxacin at different concentrations. The matrix effect was studied using a chemiluminescence method in which norfloxacin was added to an E. coli culture containing nitrate and oxygen and it was observed that the presence of nitrate and oxygen decreases the efficacy of norfloxacin. Synchronous fluorescence measurements were used to study biochemical properties, such

• Brand: Biosynth

Chemical properties

• Molecular weight: 319.33 g/mol
• Formula: C₁₆H₁₈FN₃O₃
• Purity: Min. 98 Area-%
• Color/Form: White Powder