Ofloxacin

CAS: 82419-36-1

Ref. 3D-AO26535

Product Information

• Name: Ofloxacin
• Synonyms: 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acidOfloxacineDL- 8280, (+-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, (-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazin-yl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, (3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid, (S)-(-)-Ofloxacin, (S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (+-)-, 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methylpiperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-Fluoro-2,3-dihydro-3-methyl-10-(N-methylpiperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-Fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid, Dl 8280, Exocin, Flobacin, Floxal, Floxil, Floxin, Floxin Otic, Gailuoxian, Hoe 280, Kirol, Levaquin, Levofloxacin, Levofloxacino, Levofloxacinum, Meneflox, Ocuflox, Oflicin, Oflin, Oflocet, Oflocin, Ofloren, Oflovir, Oflox, Ofloxacin Otic, Ofloxacin S-(-)-form, Ofloxacina, Ofloxacine, Ofloxacino, Ofloxacinum, Ofloxin, Oflx, Ofxin, Olfo 200, Oquin, Orf 18489, Otoxin, Oxaldin, Prifloxcin, Prifloxin, Pt 01, Sanke, Surnor, Tariferid, Tarivan, Tarivid, Traflox, Visiren, Visren, Wp 0405, Zanocin, Zenflox

Description

Ofloxacin is a fluoroquinolone antibiotic that binds to the ryanodine receptor and inhibits the voltage-gated calcium channels in gram-positive bacteria. This binding prevents the influx of calcium ions into the bacterial cell, which disrupts membrane potential and inhibits protein synthesis. Ofloxacin has been shown to be effective against oral pathogens as well as eye disorders, such as conjunctivitis, by inhibiting the polymerase chain reaction (PCR). Ofloxacin is also used to treat bacterial infections in humans, but is not active against strains with resistance mutations.

• Brand: Biosynth

Chemical properties

• Molecular weight: 361.37 g/mol
• Formula: C₁₈H₂₀FN₃O₄
• Purity: Min 98%
• Color/Form: Powder
• InChI: InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)
• InChI key: InChIKey=GSDSWSVVBLHKDQ-UHFFFAOYSA-N
• SMILES: CC1COc2c(N3CCN(C)CC3)c(F)cc3c(=O)c(C(=O)O)cn1c23