Oligomycin B
CAS: 11050-94-5
Ref. 3D-AO65695
| 2mg | To inquire | ||
| 5mg | To inquire | ||
| 10mg | To inquire | ||
| 25mg | To inquire | ||
| 50mg | To inquire |
Product Information
- (1R,2′S,4E,5′S,6S,6′S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,28S,29R)-22-Ethyl-5′,6′-dihydro-7,11,14,15-tetrahydroxy-6′-[(2R)-2-hydroxypropyl]-5′,6,8,10,12,14,16,28,29-nonamethylspiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2′-[2H]pyran]-3,3′,9,13(4′H)-tetrone
- (1S,5'R,6R,6'R,7S,8R,10S,11S,12R,14S,15R,16S,22S,25R,27R,28R,29S)-22-ethyl-7,11,14,15-tetrahydroxy-6'-[(2S)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-5',6'-dihydro-3H,9H,13H-spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-pyran]-3,3',9,13(4'H)-tetrone
- 22-ethyl-7,11,14,15-tetrahydroxy-6'-(2-hydroxypropyl)-5',6,8,10,12,14,16,28,29-nonamethyl-5',6'-dihydro-3H,9H,13H-spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-pyran]-3,3',9,13(4'H)-tetrone
- Brn 5705502
- Oligomycin A, 28-oxo-
- Spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2′-[2H]pyran]-3,3′,9,13(4′H)-tetrone, 22-ethyl-5′,6′-dihydro-7,11,14,15-tetrahydroxy-6′-(2-hydroxypropyl)-5′,6,8,10,12,14,16,28,29-nonamethyl-, [1R-[1R*,4E,5′S*,6S*,6′S*(R*),7R*,8S*,10R*,11R*,12S*,14R*,15S*,16R*,18E,20E,22R*,25S*,27S*,28S*,29R*]]-
- Spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2′-[2H]pyran]-3,3′,9,13(4′H)-tetrone, 22-ethyl-5′,6′-dihydro-7,11,14,15-tetrahydroxy-6′-[(2R)-2-hydroxypropyl]-5′,6,8,10,12,14,16,28,29-nonamethyl-, (1R,2′S,4E,5′S,6S,6′S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,28S,29R)-
Oligomycin B is a natural compound that is used as an antimicrobial agent, and it inhibits the synthesis of ATP by inhibiting ATP synthase. Oligomycin B has been shown to inhibit glutamate-induced mitochondrial membrane potential collapse in neurons. It also has therapeutic potential for treating microbial infections due to its ability to inhibit glut1, which is involved in the conversion of glucose into pyruvate. Oligomycin B also prevents the formation of disulfide bonds, which are important for protein folding, and reduces mitochondrial function.
Chemical properties
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