Product Information
5-Iodo-2-phenylthiazole is a synthetic intermediate that can be used in the Suzuki reaction. It can also be used in cross-coupling reactions with aryl halides, heterocycles, and heteroaromatic compounds. 5-Iodo-2-phenylthiazole undergoes electrophilic substitution at the thiazole ring to give a 1,2,4-triazole derivative. The optimal conditions for this reaction are as follows:
Temperature: 60 ˚C
Time: 24 hours
Reagent/solvent: Pd(PPh3)4 (5 mol%), CBr4 (1 mol%), THF (1 L), water (0.5 mL)
The following guideline should also be considered when performing this reaction:
"The use of an excess of palladium reagent is necessary."
Chemical properties
Technical inquiry about: 3D-AQB02907 5-Iodo-2-phenylthiazole
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