Rolitetracycline

CAS: 751-97-3

Ref. 3D-AR29566

Product Information

• Name: Rolitetracycline
• Synonyms: N-(Pyrrolidinomethyl)-tetracycline, (2Z,4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-2-{hydroxy[(pyrrolidin-1-ylmethyl)amino]methylidene}-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione, (2Z,4S,6S,12aS)-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-2-{hydroxy[(pyrrolidin-1-ylmethyl)amino]methylidene}-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione, (4S,4aS,5aS,6S,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-N-(1-pyrrolidinylmethyl)-2-naphthacenecarboxamide, (4S,4aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-N-(pyrrolidin-1-ylmethyl)-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-N-(1-pyrrolidinylmethyl)-, 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-N-(1-pyrrolidinylmethyl)-, (4S,4aS,5aS,6S,12aS)-, 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-N-(1-pyrrolidinylmethyl)-, [4S-(4α,4aα,5aα,6β,12aα)]-, 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-N-(1-pyrrolidinylmethyl)-2-naphthacenecarboxamide, 4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-N-(pyrrolidin-1-ylmethyl)-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, Abricycline, Bristacin, N-(1-Pyrrolidinylmethyl)tetracycline, N-(Pyrrolidinomethyl)tetracycline, N-(pyrrolidin-1-ylmethyl)tetracycline, Pyrrolidinylmethyltetracycline, Reverin, Rolitetraciclina, Rolitetracyclin, Sq 15659, Superciclin, Synotodecin, Syntetrin, Tetraverin, Transcycline, Velacycline

Description

Rolitetracycline is a tetracycline antibiotic that binds to the ribosome and inhibits protein synthesis by preventing the attachment of amino acids. It also inhibits cell division, leading to cell death. Rolitetracycline has been shown to be effective against antibiotic-resistant strains such as Methicillin-resistant Staphylococcus aureus (MRSA) and erythromycin-resistant Mycobacterium tuberculosis. Rolitetracycline has also been shown to be effective against autoimmune diseases, such as rheumatoid arthritis, psoriasis, and systemic lupus erythematosus. Rolitetracycline is used in pluripotent cells for surface methodology. The rate constant for binding to the ribosome was measured using titration calorimetry. The drug has inhibitory properties against molecular targets such as methyl ethyl coenzyme A reductase, which occurs at high concentrations

• Brand: Biosynth

Chemical properties

• Molecular weight: 527.57 g/mol
• Formula: C₂₇H₃₃N₃O₈
• Purity: Min. 95%
• Color/Form: Powder