Spiramycin I
CAS: 24916-50-5
Ref. 3D-AS16859
| 1g | 353.00 € | ||
| 2g | 471.00 € | ||
| 100mg | 141.00 € | ||
| 250mg | 177.00 € | ||
| 500mg | 237.00 € |
Product Information
- 9-O-[(2R,5S,6R)-5-(Dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]leucomycin VForomacidin ASpiramycin A
- Oxacyclohexadecane, leucomycin V deriv.
- Leucomycin V, 9-O-[(2R,5S,6R)-5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]-
- Spiramycin A
- Foromacidin A
- Leucomycin V, 9-O-[5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]-, [9(2R,5S,6R)]-
Spiramycin I is a macrolide antibiotic that inhibits the growth of bacteria by binding to the 50S ribosomal subunit. It is used in veterinary medicine to treat respiratory infections caused by Clostridium perfringens and other bacteria. Spiramycin I has been shown to inhibit bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Spiramycin I also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.
Chemical properties
Technical inquiry about: 3D-AS16859 Spiramycin I
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