Product Information
BMS-8 is a monoclonal antibody that binds to the death ligand, TNF-α. It has been shown to be effective in treating cancer cells that have an overactive PD-1 pathway, which leads to cell death by inhibiting the production of proteins vital for cell division. BMS-8 has also been shown to inhibit the activity of ctla-4 and pd-l1, molecules that are involved in the TNF-α pathway. The binding of BMS-8 to these molecules has been shown to inhibit their activation and downstream signaling pathways.
Chemical properties
Technical inquiry about: 3D-ASC20190 BMS-8
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