Thienamycin

CAS: 59995-64-1

Ref. 3D-AT168178

Product Information

• Name: Thienamycin
• Synonyms: (+)-Thienamycin, (5R,6S)-3-[(2-Aminoethyl)thio]-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, (5R,6S)-3-[(2-Ammonioethyl)sulfanyl]-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate, 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[(2-aminoethyl)thio]-6-(1-hydroxyethyl)-7-oxo-, [5R-[5α,6α(R*)]]-, 1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[(2-aminoethyl)thio]-6-[(1R)-1-hydroxyethyl]-7-oxo-, (5R,6S)-, 5-22-07-00446, 59995-64-1, Thienpenem, [5R-[5a,6a(R*)]]-3-[(2-Aminoethyl)thio]-6-(1-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid

Description

Thienamycin is a pharmaceutical drug that belongs to the class of antimicrobial agents and is used in combination with other antibiotics for the treatment of infectious diseases. It is active against gram-positive bacteria, such as penicillin-binding protein (PBP) which is found in the cell wall of these organisms. Thienamycin inhibits bacterial growth by binding to PBP, leading to cell lysis. Thienamycin has also been shown to be effective against some gram-negative species, such as E coli K-12. This antibiotic binds to the PBPs on the surface of cells and prevents them from functioning correctly, inhibiting protein synthesis and causing cell death. Thienamycin has shown pharmacokinetic properties that are pH dependent, with high values at acidic pH levels and low values at alkaline pH levels.

• Brand: Biosynth

Chemical properties

• Molecular weight: 272.32 g/mol
• Formula: C₁₁H₁₆N₂O₄S
• Purity: 80%Min
• Color/Form: Powder
• InChI: InChI=1S/C11H16N2O4S/c1-5(14)8-6-4-7(18-3-2-12)9(11(16)17)13(6)10(8)15/h5-6,8,14H,2-4,12H2,1H3,(H,16,17)/t5?,6-,8?/m1/s1
• InChI key: InChIKey=WKDDRNSBRWANNC-NAJVVJGSSA-N
• SMILES: CC(O)C1C(=O)N2C(C(=O)O)=C(SCCN)C[C@H]12