Telavancin

CAS: 372151-71-8

Ref. 3D-AT58720

Product Information

• Name: Telavancin
• Synonyms: Arbelic
• Brand: Biosynth
• Description: Telavancin is a lipoglycopeptide antibiotic, which is a semi-synthetic derivative of vancomycin. Its source is derived through modifications of the glycopeptide antibiotic, specifically aimed to enhance antibacterial activity. Telavancin functions by inhibiting cell wall synthesis in Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). It does this by binding to the D-alanyl-D-alanine terminus of cell wall precursors, disrupting peptidoglycan polymerization and, consequently, cell wall integrity. Additionally, Telavancin increases membrane permeability and disrupts membrane potential, further enhancing its bactericidal activity.

Chemical properties

• Molecular weight: 1,755.64 g/mol
• Formula: C₈₀H₁₀₆Cl₂N₁₁O₂₇P
• Purity: Min. 95%