Telavancin HCl

CAS: 560130-42-9

Ref. 3D-AT76368

Product Information

• Name: Telavancin HCl
• Synonyms: (3S,6R,7R,22R,23S,26S,36R,38aR)-3-(2-Amino-2-oxoethyl)-10,19-dichloro-44-((2-O-(3-((2-(decylamino)ethyl)amino)-3-C-methyl-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyl)oxy)-7,22,28,30,32-pentahydroxy-6-(((2R)-4-methyl-2-(methylamino)pentanoyl)amino)-2,5,24,38,39-pentaoxo-29-(((phosphonomethyl)amino)methyl)-2,3,4,5,6,7,23,24,25,26,36,37,38,38a-tetradecahydro-8,11:18,21-dietheno-23,36-(iminomethano)-22H-13,16:31,35-dimetheno-1H,13H-(1,6,9)oxadiazacyclohexadecino(4,5-m)(10,2,16)benzoxadiazacyclotetracosine-26-carboxylic acid monohydrochloride, Td 6424, Unii-0701472Zg0, Vancomycin, N3'-(2-(decylamino)ethyl)-29-(((phosphonomethyl)amino)methyl)-, monohydrochloride, Vancomycin, N^3′′-[2-(decylamino)ethyl]-29-[[(phosphonomethyl)amino]methyl]-, hydrochloride (1:1), Vancomycin, N^3′′-[2-(decylamino)ethyl]-29-[[(phosphonomethyl)amino]methyl]-, monohydrochloride, Vibativ

Description

Telavancin (TLV) is a novel lipoglycopeptide antibiotic that inhibits bacterial cell wall synthesis by binding to the peptidoglycan and inhibiting the cross-linking of peptidoglycan strands. Telavancin is active against most gram-positive bacteria, including MRSA, vancomycin-resistant enterococci, and penicillin-resistant pneumococci. It has shown efficacy in treating infections caused by drug-resistant Streptococcus pneumoniae and Enterococcus faecium. Telavancin also has activity against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus faecalis (VRE). Telavancin is not effective against gram-negative bacteria such as Escherichia coli or Pseudomonas aeruginosa, but does have some activity against Mycoplasma species.

• Brand: Biosynth

Chemical properties

• Molecular weight: 1,792.1 g/mol
• Formula: C₈₀H₁₀₆Cl₂N₁₁O₂₇P·HCl
• Purity: (%) Min. 92%
• Color/Form: White Powder