Product Information
BI-2852 is a drug binding inhibitor that is selective for the protein kinases of the Src family and inhibits the phosphorylation of tyrosine residues on these proteins. BI-2852 binds to and blocks the ATP-binding site on these enzymes, preventing their activation. This compound was shown to inhibit cancer cell growth in vitro and in vivo, by inducing cell cycle arrest and apoptosis. BI-2852 has been shown to be an allosteric inhibitor, activating the enzyme at lower concentrations than those required for the classical inhibitors. It also inhibits protein synthesis by binding to and inhibiting ribosomes in bacteria.
Chemical properties
Technical inquiry about: 3D-AVD48251 BI-2852
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