CSN5i-3
CAS: 2375740-98-8
Ref. 3D-AVD74098
| 1mg | 840.00 € | ||
| 5mg | 2,234.00 € | ||
| 10mg | 3,574.00 € | ||
| 25mg | 6,702.00 € | ||
| 50mg | 10,723.00 € |
Product Information
CSN5i-3 is a small molecule that inhibits the ubiquitin-proteasome system. It has potent antitumor activity in vitro and in vivo, as well as anti-inflammatory effects. CSN5i-3 is a selective inhibitor of the E1 enzyme (ubiquitin ligase) and has been shown to inhibit the proteasomal degradation of prostate cancer cells. CSN5i-3 also has pharmacokinetic properties that are favorable for clinical development and it can be used to treat hepatic steatosis and bone cancer. CSN5i-3 is active against infectious diseases such as malaria, tuberculosis, and HIV by inhibiting host protein synthesis.
Chemical properties
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