CSN5i-3

CAS: 2375740-98-8

Ref. 3D-AVD74098

Product Information

• Name: CSN5i-3
• Brand: Biosynth
• Description: CSN5i-3 is a small molecule that inhibits the ubiquitin-proteasome system. It has potent antitumor activity in vitro and in vivo, as well as anti-inflammatory effects. CSN5i-3 is a selective inhibitor of the E1 enzyme (ubiquitin ligase) and has been shown to inhibit the proteasomal degradation of prostate cancer cells. CSN5i-3 also has pharmacokinetic properties that are favorable for clinical development and it can be used to treat hepatic steatosis and bone cancer. CSN5i-3 is active against infectious diseases such as malaria, tuberculosis, and HIV by inhibiting host protein synthesis.

Chemical properties

• Molecular weight: 505.6 g/mol
• Formula: C₂₈H₂₉F₂N₅O₂
• Purity: Min. 95%