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NDI-091143
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NDI-091143

CAS: 2375840-87-0

Ref. 3D-AVD84087

50mgTo inquire
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Estimated delivery in United States, on Thursday 16 Jan 2025

Product Information

Name:
NDI-091143
Description:

NDI-091143 is a drug that inhibits prenylation, which is the process whereby proteins are modified by the attachment of a chain of seven carbon atoms called an isoprenoid. This process is important for cancer cell survival and the maintenance of healthy cells. Inhibiting this process leads to apoptosis, or cell death, in cancer cells. NDI-091143 has been shown to have potent inhibition against acetylated proteins in vitro. The drug has also been shown to be hydrophobic and druggable, meaning it can cross the blood brain barrier and enter cells. Additionally, NDI-091143 has been found to bind to cavity surfaces in cryo-electron microscopy studies. The drug inhibits cancer cell growth by binding to a specific site on HMG CoA reductase which results in reduced levels of cholesterol synthesis.
NDI-091143's mechanism of action involves inhibiting the enzyme 3β-hydroxyster

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
453.84 g/mol
Formula:
C20H14ClF2NO5S
Purity:
Min. 95%
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Hazard Info

UN Number:
EQ:
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Forbidden to fly:
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LQ:

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