Product Information
Name:Borussertib
Controlled Product
Brand:Biosynth
Description:Borussertib is a molecule that inhibits the transcriptional regulator aurora kinase A. It has been shown to be an effective anticancer drug in animal models and in human cancer cells in vitro. Borussertib inhibits cell growth by binding to the tumor suppressor protein p53, which prevents it from initiating apoptosis. Borussertib also causes cell lysis by inhibiting the production of RNA and proteins, leading to cell death. Borussertib has been shown to inhibit metastatic colorectal cancer, cervical cancer, and cancer cell viability in vitro. The mechanism of action may be due to inhibition of aurora kinase A-mediated phosphorylation of p53 or inhibition of aurora kinase A-mediated phosphorylation of retinoblastoma protein (pRb).
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:596.7 g/mol
Formula:C36H32N6O3
Purity:Min. 95%
Technical inquiry about: Borussertib
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