6-Bromo-2-naphthyl-α-D-mannopyranoside

CAS: 28541-84-6

Ref. 3D-B-8930

Product Information

• Name: 6-Bromo-2-naphthyl-α-D-mannopyranoside
• Synonyms: 2-(6-Bromonaphthyl)-alpha-D-mannopyranoside, 6-Bromo-2-naphthalenyl α-<span class="text-smallcaps">D</span>-mannopyranoside, 6-Bromo-2-naphthyl α-<span class="text-smallcaps">D</span>-mannopyranoside, 6-Bromonaphthalen-2-Yl Hexopyranoside, 6-bromonaphthalen-2-yl alpha-D-mannopyranoside, Mannopyranoside, 6-bromo-2-naphthyl, α-<span class="text-smallcaps">D</span>-, α-<span class="text-smallcaps">D</span>-Mannopyranoside, 6-bromo-2-naphthalenyl, 6-Bromo-2-naphthyl alpha-D-mannopyranoside, α-D-Mannopyranoside, 6-bromo-2-naphthalenyl, 6-Bromo-2-naphthyl α-D-mannopyranoside, 6-Bromo-2-naphthalenyl α-D-mannopyranoside, Mannopyranoside, 6-bromo-2-naphthyl, α-D-

Description

6-Bromo-2-naphthyl-alpha-D-mannopyranoside is a strong inhibitor of alpha-mannosidase. It has been shown to inhibit the growth of Mycobacterium tuberculosis and Streptococcus pneumoniae, which are both known to cause bacterial infections in humans. 6BNA inhibits the enzyme alpha-mannosidase, which hydrolyzes terminal α-(1,4)-linked mannose residues from oligosaccharides and glycoproteins. This drug has a high affinity for the active site of alpha-mannosidase and an IC50 value of 0.2 mM, making it an effective inhibitor.

• Brand: Biosynth

Chemical properties

• Molecular weight: 385.22 g/mol
• Formula: C₁₆H₁₇BrO₆
• Purity: Min. 98.0 Area-%