Product Information
- Diamidafos [ANSI:ISO]
- Diamidfos
- Nellite
- Ai3-27222
- Brn 0880587
- Caswell No. 654B
- Diamidafos [ANSI]
- Diamidaphos
- Diamidofos
- Dowco 169
- See more synonyms
- EPA Pesticide Chemical Code 102101
- Hsdb 1751
- O-Phenyl-N,N'-dimethyl phosphorodiamidate
- Phosphorodiamidic acid, N,N'-dimethyl-, phenyl ester
Diamidafos is a potent anticancer drug that has been used in Chinese traditional medicine to treat tumors. It acts as a protein kinase inhibitor, preventing the phosphorylation of proteins involved in cell growth and survival. Diamidafos is an analog of staurosporine, one of the first protein kinase inhibitors discovered. It has been shown to induce apoptosis in cancer cells by inhibiting the activity of various kinases. Diamidafos has also been found to inhibit the growth of human cancer cells and reduce tumor size in animal models. In addition, it can be administered orally and is excreted primarily through urine. To improve its efficacy, diamidafos can be combined with chitosan, a natural polymer that enhances drug delivery and bioavailability.
Chemical properties
Technical inquiry about: 3D-BAA75458 Diamidafos
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