Product Information
- (2S)-2-hydroxy-3-phenylpropanoic acid
- 1-Pentyne, 5-phenyl-
- 1-Phenyl-4-pentyne
- 4-Pentyn-1-ylbenzene
- 4-Pentynylbenzene
- Benzene, 4-pentyn-1-yl-
- Benzene, 4-pentynyl-
- NSC 102794
- Pent-4-Yn-1-Ylbenzene
- Pent-4-ynylbenzene
- See more synonyms
5-Phenyl-1-pentyne is a reactive compound that inhibits the uptake of naphthalene in human liver cells. It has been shown to inhibit monooxygenase activity, which prevents the formation of reactive oxygen species and lipid peroxidation. The molecular modeling study suggests that 5-phenyl-1-pentyne binds to a hydroxyl group on the enzyme's active site. This binding prevents the enzyme from binding with its substrate, thereby inhibiting metabolism. In addition, this chemical inhibitor has an inhibitory effect on wild type mice and CD-1 mice. Low energy chemical inhibitors are also able to inhibit the metabolism of rat liver microsomes.
Chemical properties
Technical inquiry about: 3D-BAA82314 5-Phenyl-1-pentyne
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