Picrasin B
CAS: 26121-56-2
Ref. 3D-BBA12156
| 1mg | To inquire | ||
| 5mg | To inquire | ||
| 10mg | To inquire | ||
| 25mg | To inquire | ||
| 50mg | To inquire |
Product Information
- Picras-12-ene-1,11,16-trione, 2-hydroxy-12-methoxy-, (2α)-
- Phenanthro[10,1-bc]pyran-1,5,11(4H)-trione, 3aβ,6aβ,7,7aα,8,9,10,11a,11bα,11c-decahydro-10α-hydroxy-2-methoxy-3,8α,11aβ,11cβ-tetramethyl-
- Nigakilactone I
- (2α)-2-Hydroxy-12-methoxypicras-12-ene-1,11,16-trione
Picrasin B is a quassinoid that is extracted from the bark of the Picrasma quassioides tree. It has been shown to have anti-malarial activity in humans and has been used as a component of traditional medicines in Africa. Picrasin B can be demethylated by alkaline hydrolysis to neoquassin, which is a potent cytotoxic agent against cancer cells. The structure of picrasin B is similar to that of other quassinoids, such as quassia and rhynchophylline. These compounds are monoterpenes with a skeleton that consists of six carbons, five hydroxyls, and two methyl groups on two adjacent carbons. The active metabolite of picrasin B is neoquassin, which can be obtained through demethylation or chlorination.
Chemical properties
Technical inquiry about: 3D-BBA12156 Picrasin B
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