Product Information
Name:CHIR 99021 hydrochloride
Brand:Biosynth
Description:Potent and selective inhibitor of the glycogen synthase kinase GSK-3. Promotes cell renewal in embryonic stem cells by modulating Notch, MAPK and TGF-β signalling pathways, which are involved in pluripotency. It also affects the Wnt/β-catenin pathway and alters expression of genes coding for proteins, epigenetic regulatory elements and non-coding RNAs. The combination of CHIR 99021 and basic fibroblast growth factor (bFGF) allows long-term self-renewal in adult mouse retinal progenitor cells.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:501.8 g/mol
Formula:C22H18Cl2N8·HCl
Purity:Min. 95%
Technical inquiry about: CHIR 99021 hydrochloride
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