Product Information
10, 11-Dehydrocurvularin is a naturally occurring sesquiterpene that has been shown to have strong antiproliferative and proapoptotic activities against cancer cells. It also inhibits the transcriptional activity of signal transducer and activator of transcription 3 (STAT3), which is a transcription factor for genes involved in cellular proliferation. 10, 11-Dehydrocurvularin induces apoptosis through the induction of reactive oxygen species and mitochondrial dysfunction. 10, 11-Dehydrocurvularin also has been shown to be cytotoxic to human tumor cell lines in culture. This compound may be useful in cancer therapy due to its ability to inhibit STAT3.
Chemical properties
Technical inquiry about: 3D-BD162702 10, 11-Dehydrocurvularin
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