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Nicainoprol
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Nicainoprol

CAS: 76252-06-7

Ref. 3D-BDA25206

1mgDiscontinued
5mgDiscontinued
10mgDiscontinued
25mgDiscontinued
50mgDiscontinued

Discontinued product. For inquiries about similar products, please fill out our form or email us at support@cymitquimica.com.


Product Information

Name:
Nicainoprol
Synonyms:
  • (+-)-1,2,3,4-Tetrahydro-8-(2-hydroxy-3-(isopropylamino)propoxy)-1-nicotinoylquinoline
  • 1,2,3,4-Tetrahydro-8-(2-hydroxy-3-(isopropylamino)propoxy)-1-(3-pyridylcarbonyl)quinoline
  • Methanone, [3,4-dihydro-8-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-1(2H)-quinolinyl]-3-pyridinyl-
  • Nicainoprol [INN]
  • Nicainoprolum
  • Nicainoprolum [INN-Latin]
  • Quinoline, 1,2,3,4-tetrahydro-8-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-1-(3-pyridinylcarbonyl)-
  • Unii-1Ua960P80H
  • [3,4-Dihydro-8-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-1(2H)-quinolinyl]-3-pyridinylmethanone
  • {8-[2-hydroxy-3-(propan-2-ylamino)propoxy]-3,4-dihydroquinolin-1(2H)-yl}(pyridin-3-yl)methanone
  • See more synonyms
Description:

Nicainoprol is a cardiac glycoside that is used as an anti-arrhythmic agent. It binds to the phospholipid membranes of cardiac muscle cells and inhibits the enzyme creatine kinase, which is necessary for the transfer of high-energy phosphate groups in the myocardium. This inhibition leads to a decrease in the rate at which ATP is synthesized. Nicainoprol has dose-dependent effects on cardiac function, with low doses causing an inhibitory effect and higher doses inducing proarrhythmia. The mechanism of nicainoprol’s action has been elucidated by kinetic data obtained from reconstituted preparations and from erythrocyte ghosts incubated with this drug. Nicainoprol also inhibits fatty acid oxidation in skeletal muscle cells, leading to increased levels of acetyl-CoA and citrate in these cells.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
369.46 g/mol
Formula:
C21H27N3O3
Purity:
Min. 95%
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
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P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

Inquiry about discontinued product: 3D-BDA25206 Nicainoprol

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