Product Information
- (4-Chlorophenyl)(dimethoxyphosphinyl)methyl phosphoric acid dimethyl ester
- Brn 5985350
- Clenicor
- Dimethyl (p-chloro-alpha-hydroxybenzyl)phosphonate, dimethyl phosphate
- Dimethyl alpha-(dimethoxyphosphinyl)-p-chlorobenzyl phosphate
- Dimethyl {(4-Chlorophenyl)[(Dimethoxyphosphoryl)Oxy]Methyl}Phosphonate
- Mifobate [USAN:INN]
- Mifobato
- Mifobato [Spanish]
- Mifobatum
- See more synonyms
- Mifobatum [Latin]
- Phosphoric acid, (4-chlorophenyl)(dimethoxyphosphinyl)methyl dimethyl ester
- Sr 202
- Unii-Zka4Ovv12E
Mifobate is a fatty acid that is structurally similar to prostaglandin E2. It has been shown to inhibit the activation of caspase-1 and increase mitochondrial membrane potential in cells with oxidative injury. It also reduces insulin sensitivity in wild-type mice but not in transgenic animals. Mifobate can be used as a pharmaceutical dosage for the treatment of obesity, type 2 diabetes, and metabolic syndrome. Mifobate binds to Toll-like receptor 4 (TLR4) on human monocytes and inhibits peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC1α) activity. This inhibition leads to reduced insulin sensitivity and increased fatty acid release from adipose tissue.
Chemical properties
Technical inquiry about: 3D-BDA54172 Mifobate
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