Ac710 mesylate
CAS: 1351522-05-8
Ref. 3D-BEC52205
1mg | To inquire | ||
5mg | To inquire | ||
10mg | To inquire | ||
25mg | To inquire | ||
50mg | To inquire |
Product Information
- 2-Pyridinecarboxamide, N-[4-[[[[5-(1,1-dimethylethyl)-3-isoxazolyl]amino]carbonyl]amino]phenyl]-5-[(1-ethyl-2,2,6,6-tetramethyl-4-piperidinyl)oxy]-, methanesulfonate (1:1)
Ac710 mesylate is a small molecule that is being developed for the treatment of fibrosis. It blocks the activity of collagen-specific TGF-β1 and TGF-β3, which are cytokines that function as signaling molecules in fibrosis. Ac710 mesylate has been shown to inhibit alveolar type II cell proliferation and induce lung fibrosis in mice. The drug was also shown to prevent emphysema development in rats with chronic bronchitis, by reducing protein expression and neutrophil infiltration.
Chemical properties
Technical inquiry about: 3D-BEC52205 Ac710 mesylate
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