Product Information
- 2,5-Dichloro-3-cyanopyridine
- 2,5-Dichloro-3-pyridinecarbonitrile
- 2,5-Dichloropyridine-3-carbonitrile
- 3-Pyridinecarbonitrile, 2,5-dichloro-
- T6Nj Bg Ccn Eg
2,5-Dichloronicotinonitrile is a phosphoinositide analog that has been shown to have cytotoxic effects in cancer cells. It binds to the phosphate groups on the cell membrane and inhibits the synthesis of phosphatidylinositol-3,4,5-trisphosphate (PIP3). This prevents the activation of Akt, which is a protein involved in cell survival and proliferation. The molecular modelling study showed that 2,5-Dichloronicotinonitrile can inhibit cancer cell proliferation at low nanomolar concentrations.
Chemical properties
Technical inquiry about: 3D-BFA95466 2,5-Dichloronicotinonitrile
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